Piers Morgan travels across America to meet some of the country's most notorious female killers in a quest to discover what drives women to kill.
Over two series Piers meets Erin Caffey who, at the age of 16, masterminded the brutal murder of her entire family. In Florida he meets Ashley Humphrey, who despite admitting the cold-blooded slaughter of a woman she'd never met, will walk free after serving only 25 years; Jennifer Mee, who at the age of 15 was a global celebrity thanks to a case of persistent hiccups but now faces a lifetime behind bars for a murder she didn't commit; and in New York state Piers meets Sheila Davalloo, a high-flying executive driven by lust and jealousy to kill her lover's girlfriend.